The PrlVmDev_Connect function allows to connect virtual devices while the virtual machine is running.
PRL_HANDLE PrlVmDev_Connect( PRL_HANDLE hVmDev );
PrlApiVm.h
A handle of type PHT_JOB containing the results of this asynchronous operation or PRL_INVALID_HANDLE if there's not enough memory to instantiate the job object.
To get the return code from the PHT_JOB object, use the PrlJob_GetRetCode function. Possible values are:
PRL_ERR_INVALID_ARG - invalid handle was passed.
PRL_ERR_SUCCESS - function completed successfully.